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Background Several studies are ongoing to obtain more information about post-COVID-19 (corona virus disease-19) pulmonary fibrosis. Old-aged patients are more likely to evolve lung fibrosis in COVID-19. Another risk factor is the degree of disease severity, including comorbidities, such as hypertension, diabetes, as well as lab findings, for example, lymphopenia and leukocytosis. Aims of work To assess the prevalence of post-COVID-19 pulmonary fibrosis and reveal some of its predictors. Results The study included 50 patients in the outpatient clinics of Chest and EL-Helal Hospitals with a mean age of 49.6 +/- 17.7 years. It included 32 (64%) males and 18 (36%) females. Pulmonary fibrosis was detected in 34 (68%) patients. Pulmonary fibrosis was bilateral in 24 patients and unilateral in 10 patients. Leucopenia, elevated serum ferritin, elevated D-dimer, and elevated C-reactive protein (CRP) were associated with pulmonary fibrosis (P value 0.001). Conclusion Pulmonary fibrosis is recognized as a complication between survivors. Immune response due to lung injury by viral infection, and trials to repair are keys to the procedure of fibro genesis. Predictors of lung fibrosis involve increased lab parameters such as serum ferritin, C-reactive protein, and D-dimer. Copyright © 2022 The Egyptian Journal of Chest Diseases and Tuberculosis.
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Purpose: To offer an insight into post-COVID-19 Industry 5.0 environment, educational responses that are being made by Higher Education institutions (HEIs), and leadership qualities that appear to be effective in this environment. Also, to develop a conceptual model of causal relationships between the identified constructs in producing educational curricular outcomes. Design/methodology/approach: Interpretative review was conducted identifying, analyzing and synthesizing the relevant literature on the relationships between post-COVID-19 Industry 5.0 environment, HEI’s leadership characteristics, their decision-making bases and curricular design outcomes. Findings: The literature showed that in unpredictable post-COVID-19 Industry 5.0 environment, thriving HEIs are found to have leaders who are perceptive, visionary and agile with effective communication and navigation skills;embracing change culture;and able to learn from concrete experiences. Responding to the pandemic and Industry 5.0’s disruptive technology, these leaders are accelerating university–industry engagement and developing more flexible, student-centered, work-based curricula. Synthesis of the literature resulted in developing a conceptual model that shows that environmental turbulence is likely to influence curriculum design through leaders’ decision bases, and that leaders’ characteristics and industry engagement may interact with leaders’ decision bases to strengthen this influence. Originality/value: A different lens was offered of the type of leadership that is seen to be effective in the turbulent and HE post-COVID-19 Industry 5.0 environment, and a novel conceptual model of relationships was developed which has potential impacts for HE leadership theory and practice. © 2022, Emerald Publishing Limited.
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Objective: Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus, the first cases of which were reported in Wuhan, China in December 2019. The disease often presents with major respiratory symptoms. In addition, gastrointestinal (GI) symptoms are observed. They may be the first or even the only symptoms of the disease. The aim of this study is to demonstrate the presentation of GI symptoms and their relationship to other symptoms, the clinical course and prognosis of patients with COVID-19. Methods: Included in this study were patients over 18 years of age who had been hospitalised for treatment in clinics and intensive care units due to COVID-19 between March and June 2020. The symptoms reported by the patients at the time of admission and the data collected as a result of the clinical follow-up were evaluated. Results: Out of the 1,045 patients with COVID-19, 140 patients (13.4%) had GI symptoms. The complaints of these 140 patients were nausea (53.6%), vomiting (32.1%), abdominal pain (11.4%), diarrhea (45.7%), anorexia (43.6%) and loss of taste (5.6%). In 3.2% of the patients, only GI symptoms were present, without any respiratory symptoms. Conclusion: Gastrointestinal symptoms were present at the time of admission in 13.4% of the patients with COVID-19. The most common GI symptom in the patients was nausea. Length of stay in hospital and mortality rate were higher in patients with only GI symptoms. Therefore, GI symptoms should be considered in patients with suspected COVID-19.
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BACKGROUND AND AIMS: Fabry disease is a rare metabolic disorder, lifelong enzyme replacement therapy with recombinant human alpha-galactosidase A (agalsidase) constituted the cornerstone of disease-specific therapy. COVID-19 pandemic and epidemic control measures including lockdowns impaired access to health care services. We examined the effect of COVID-19 pandemic and lockdown measures on mood status and management of Fabry disease patients. METHOD: We conducted a cross-sectional study between October 2020 and December 2020. We used the Hospital Anxiety and Depression Scale (HADS) to evaluate the mood statuses of FD patients and the Morisky Medication Adherence Scale (MMAS-4) to assess patient adherence.We also examined age and sex-matched control group to compare mood status. RESULTS: A total of 68 (Male 48.5 %, mean age 37.0) FD patients were under regular follow-up in our institution, 59 of those patients were taking ERT every other week. Two of our patients had reported having a COVID-19 infection, and both of them recovered. 25 patients reported to miss an ERT for a median of one dose, 16 of these 25 patients have reported that they did not come to the hospital because of infection fear. Half of the patients had adopted home-based infusion;they arranged a nurse for homebased infusion therapy by their own means. According to MMAS-4 FD patients had good adherence to their therapy (Median score 0, range 0-2). Mood status of FD patients and controls are shown in Table 1. Both HADS depression and anxiety scores were higher in the control group compared to FD patients. Additionally, abnormal scores were more prevalent for HADS depression scores in controls (Figure 1). CONCLUSION: We found that the mood status of FD patients was better than the control group. Traumatic growth may be an important factor to explain this finding. Their adherence to therapy was good. Home-based therapy was the preferred method by the patients. Government-supported home therapy programs might be beneficial for FD patients to increase adherence to the therapy. (Table Presented).